Advanced Technology


Using a speculum to gain access, a tiny instrument is inserted into the uterus to ‘scratch’ the uterine lining. 

What is Mechanical Endometrial Injury (MEI)? 

Mechanical Endometrial Injury (MEI) is a simple procedure performed on the endometrial lining by one of the Fertility Doctors at Fertility North.  

During an MEI, the lining of the uterus (the endometrium) is gently scratched by a thin catheter called a pipelle. This mechanical injury, the scratch, is reported to cause:  

  • A repair response by the body, and growth factors, hormones and chemicals infiltrate the injured area. When the uterine lining repairs and regrows, it is thought that it is more receptive to implantation.  
  • The switching on of certain genes that help prepare the endometrium for possible implantation.  

Who is an MEI suitable for? 

At Fertility North, MEI is used to treat patients who have experienced:  

  • Recurrent implantation failure following IVF, ICSI and FET. 
  • Recurrent miscarriage.  

It may be used in other patients, at the discretion of their Fertility Doctor.  

What does an MEI procedure involve?

An MEI takes place in the mid-luteal phase of your menstrual cycle (the second half, after ovulation but before your period).  Using a speculum to gain access, a tiny instrument is inserted into the uterus to ‘scratch’ the uterine lining 

How is an MEI done?

The Mechanical Endometrial Injury procedure is similar to a pap smear and is carried out in the treatment room at Fertility North by one of our Fertility Doctors.  

MEI Pre-Planning?

When you book to have an MEI, it will add a month onto your treatment cycle, so please ensure you allow time for this.  

Are there any risks or pain associated with an MEI? 

Most patients experience some mild lower-abdominal cramping during and just after the procedure.  Consequently, Fertility North recommends the use of an over-the-counter pain relief, such as Paracetamol, prior to undertaking your MEI.  Should the cramping continue when you return home, you can use a heat pack to relieve discomfort. 

The preparation and procedure of MEI are all done aseptically to reduce the risk of introducing infection. Like all procedures a very small risk of infection is still present. 

How can we help you? 

While MEI has been shown to help some patients in conceiving, it is not suitable for use in all patients.  Your Doctor will discuss your suitability for MEI in accordance with your individual circumstances.  

If prescribed, our Nursing Team will then help you with planning your treatment – MEI must be done in conjunction with a treatment cycle order for it to have its best effect.    

To arrange an appointment or to find out more, please contact the team at Fertility North. 

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