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Endometrial Receptivity Analysis (ERA ® )

Fertility North is delighted to offer patients the latest in cutting edge infertility treatment and technology. ERA® is the latest new procedure we have added to our services. 

What is the Endometrial Receptivity Analysis test?

The Endometrial Receptivity Analysis (ERA®) is a diagnostic test used to determine the optimal time of a treatment cycle for embryo transfer to take place. 

During a mock embryo transfer cycle, a small sample of tissue is taken from your endometrium (the lining of the womb) using a specialised sampling kit.  Once the biopsy has been taken, it is sent to the laboratory of Igenomix, where the test was developed more than 10 years ago. 

There, the Igenomix Laboratory will analyse the more than 240 genes involved in implantation in your sample to determine your individual optimum implantation window. 

What is the purpose of an Endometrial Receptivity Analysis test?

It is thought that up to 30% of women will have a displaced window of implantation (the period of time during which an embryo is most likely to implant in the uterus.  If embryo transfer is not well-timed, even the most perfect embryo will fail to implant. 

The ERA® test evaluates the stage of an endometrium to determine whether it is receptive or non-receptive to implantation at the time the biopsy was taken.  In the case where the endometrium is non-receptive, the test identifies the ideal personalised window of implantation for each patient.  This gives us the time when the uterus will be most receptive to an embryo transfer, improving the chances of success.   

This personalised timing is then used in a subsequent frozen embryo transfer cycle to ensure that your embryo transfer takes place at the optimum time for you. 

Who is an Endometrial Receptivity test suitable for?

The ERA® test has been proven most useful for patients who have experienced recurrent implantation failure with good quality embryos.  Recurrent implantation failure (RIF) is defined as the failure to achieve a clinical pregnancy after the transfer of at least four good-quality embryos in a minimum of three fresh or frozen cycles to a woman under the age of 40 years. 

How can we help you?

Fertility North have been working in collaboration with Igenomix conducting the ERA test since 2016.  That said, it is really important to note that the ERA test cannot guarantee pregnancy, so it is important that you discuss this test and how it may (or may not) benefit you with your Fertility Doctor.  To schedule an appointment or to find out moreplease contact the team at Fertility North.